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WHO has launched a new network for coronaviruses, CoViNet, to facilitate and coordinate global expertise and capacities for early and accurate detection, monitoring and assessment of SARS-CoV-2, MERS-CoV and novel coronaviruses of public health importance.

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Winter Coronavirus (COVID-19) Infection Study: estimates of epidemiological characteristics, 14 March 2024

© Crown copyright 2024 This publication is licensed under the terms of the Open Government Licence v3.0 except where otherwise stated. To view this licence, visit nationalarchives.gov.uk/doc/open-government-licence/version/3 or write to the Information Policy Team, The National Archives, Kew, London TW9 4DU, or email: [email protected]. Where we have identified any third party copyright information you will need to obtain permission from the copyright holders concerned.

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Lab-made SARS-CoV-2 study prompts gain-of-function questions

Media reports about work on a hybrid SARS-CoV-2 virus at a Boston University's biosafety level 3 (BSL-3) lab have inflamed more controversy about lab biosafety and raised questions about federal oversight, following the publication of the research team's preprint (not peer-reviewed) study that described their findings.

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The big challenge right now is…: WHO on what could hinder COVID endgame

#COVID19 in all countries, but the pandemic is not over and we still have a lot of work to do.So many tools exist that ⬇️ the spread of SARS-CoV-2, prevent long term consequences & save lives.We can do this.

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Why Delta is the deadliest COVID variant?

Of all the COVID variants, Delta is the deadliest one, a new study has revealed. Five different coronavirus variants were studied for the research that include Alpha, Delta, and three others that emerged before Alpha.

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SARS-CoV-2 antibodies in kids after COVID may peak at 1 to 3 months

In a group of nonhospitalized children 0 to 16 years old, SARS-CoV-2 neutralizing antibody levels peaked at about 84% 1 to 3 months after they tested positive for COVID-19 but remain high for more than a year, finds a single-center study published yesterday in JAMA Pediatrics.

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Study: SARS-CoV-2 virus shedding varied widely in the mildly ill

Daily infectious SARS-CoV-2 virus shedding varied substantially among 60 newly diagnosed asymptomatic or mildly ill COVID-19 patients early in the pandemic, suggesting that individual differences in viral dynamics may account for "superspreading," according to a first-of-its-kind modeling study published yesterday in Nature Microbiology.

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What are Covid toes and how are they caused? Everything you need to know

Covid-19. But they accept that there is not enough evidence to rubbish the claims too.

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COVID-19 Scan for Mar 22, 2022

A US study shows that white-tailed deer (WTD) inoculated with COVID-19–causing SARS-CoV-2 shed infectious virus for up to 5 days, resulting in efficient deer-to-deer transmission on day 3, findings the authors say highlight the potential for deer to become a reservoir for the virus.Cornell University and US Department of Agriculture (US

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COVID can be transmitted from mothers to babies if…: Study reveals how to prevent infections

coronavirus from a mother to baby before, during and after childbirth is quite possible, but such cases are rare, recent studies have shown. However, transmissions are more likely to occur when the women have severe COVID-19 or were diagnosed after childbirth, the researchers pointed out adding that “less than 2% of babies born to mothers with SARS-CoV-2 infection also test positive for the virus".

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Potential new treatment for Covid-19 identified by scientists

Covid-19 treatment methods primarily focus solely on preventing the virus from replicating. However, scientists have claimed that the new treatment inhibits replication but also protects or repairs tissue, which is important because COVID-19 can cause symptoms that affect patients long after the viral infection has been cleared.

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Health groups press for more wildlife SARS-CoV-2 tracking

In a joint statement today, three global health groups urged countries to prioritize monitoring SARS-CoV-2 in wildlife, given growing concerns that continued spread could create virus reservoirs in animals.

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‘Ensure Covid don't transmit from animals to humans,’ WHO on next variant; 7 key steps to stop spread

Together we can end the #COVID19 pandemic.@WHO @FAO @OIEAnimalHealth https://t.co/LuV9WjdTQ9

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Next COVID variant can be severe as Delta, immune evasive like Omicron: Experts answer 2 key questions

Nature.

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Delta remains main Covid variant of concern in India, other strains now neglible: Govt

New Delhi: Delta variant of COVID-19 continues to be the main variant of concern and other variants of interest or concern are now negligible in sequencing data from India, the Indian Sars-CoV-2 Genomics Consortium (INSACOG) said.

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Long COVID symptoms may have causes other than SARS-CoV-2

A French study finds that, of 20 persistent physical symptoms reported by adults who said they had recovered from COVID-19, only 1 was linked to SARS-CoV-2 infection, as indicated by the presence of antibodies to the virus.

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Can we fight SARS-CoV-2 with SARS-CoV-2?

poem by Augustus De Morgan, “Great fleas have little fleas upon their backs to bite ’em, And little fleas have lesser fleas, and so ad infinitum.”It seems this is true even for viruses — the smallest of all parasites — which in turn have smaller viruses that parasitize them.Biologists at Pennsylvania State University (Penn State) in University Park have exploited this universal law of nature to create a parasite of SARS-CoV-2 that they believe could treat COVID-19.Coronaviruses, such as SARS-CoV-2, replicate by injecting their molecular blueprint, or genome — which is a single strand of RNA — into a host cell.The infected cell copies the viral genome and churns out the proteins that it encodes, which are then used to build new virus

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Oral drug successfully treats SARS-CoV-2 infections in hamsters

reduce mortality in mechanically ventilated patients by a third. Stay informed with live updates on the current COVID-19 outbreak and visit our coronavirus hub for more advice on prevention and treatment.Remdesivir can decrease the length of time a person has COVID-19 and does provide some benefit to some people, but it has little effect on its own.

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Limited protection against SARS-CoV-2 reinfection in over 65s

However, among individuals aged 65 years and older, protection against reinfection dropped to 47%.Stay informed with live updates on the current COVID-19 outbreak and visit our coronavirus hub for more advice on prevention and treatment.“Since older people are also more likely to experience severe disease symptoms, and sadly die, our findings make clear how important it is to implement policies to protect the elderly during the pandemic,” says senior study author Prof. Steen Ethelberg, Ph.D., of the Statens Serum Institut in Copenhagen, Denmark.

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Suspected Recurrent SARS-CoV-2 Infections Among Residents of a Skilled Nursing Facility During a Second COVID-19 Outbreak — Kentucky, July–November 2020

1,2; Douglas Thoroughman, PhD1,3; Holly Miranda1,4; Kevin Spicer, MD, PhD1,5 (View author affiliations)Case reports of reinfection with SARS-CoV-2 exist; however, data are limited as to the frequency and outcomes of reinfection.Five residents of a skilled nursing facility received positive SARS-CoV-2 nucleic acid test results in two separate COVID-19 outbreaks separated by 3 months. Residents received at least four negative test results between the two outbreaks, suggesting the possibility of reinfection.

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Detection of B.1.351 SARS-CoV-2 Variant Strain — Zambia, December 2020

1*; Ngonda Saasa, PhD2*; Nyambe Sinyange, MD3; George Busby, PhD4; Peter J. Chipimo, MD, PhD3; Jason Hendry, PhD4; Otridah Kapona, MSc3; Samuel Yingst, DVM, PhD5; Jonas Z.

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First Identified Cases of SARS-CoV-2 Variant B.1.1.7 in Minnesota — December 2020–January 2021

1,2; Alexandra J.

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How CDC is responding to SARS-CoV-2 variants globally

For more on Global COVID-19 activitiesSequencing is a laboratory technique that is used to read the genetic code and identify variants of SARS-CoV-2.

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mRNA vaccines may provide lower immunity to new SARS-CoV-2 variants

50% efficacy standard set by the Food and Drug Administration (FDA) for approval.However, with the emergence of new COVID variants — B.1.1.7, B.1.351, and P.1 — there is concern that these vaccines will not be as effective.A new study evaluates the effectiveness of the mRNA vaccines in their current forms against these new variants.Stay informed with live updates on the current COVID-19 outbreak and visit our coronavirus hub for more advice on prevention and treatment.The coronavirus, like many viruses, “hijacks” cells.

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Transmission of SARS-CoV-2 in K-12 schools

1 Schools also provide critical services including school meal programs and social, physical, behavioral, and mental health services.1,2 Schools have indirect benefits to the community, including enabling parents, guardians, and caregivers to work.1,3 In the spring of 2020, all public kindergarten to grade 12 (K-12) schools in the United States closed for in-person instruction as a strategy to slow the spread of SARS-CoV-2. With the beginning of the fall term 2020, K-12 schools have variably used several models of instruction, including in-person, virtual, and hybrid models of instruction.

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Maximizing Fit for Cloth and Medical Procedure Masks to Improve Performance and Reduce SARS-CoV-2 Transmission and Exposure, 2021

1; Donald H. Beezhold, PhD2; John D.

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China probe: SARS-CoV-2 jump from go-between host most likely scenario

Representatives from China and an international joint mission team led by the World Health Organization (WHO) today in Wuhan detailed the results of a 2-week probe into the zoonotic source of the outbreaks, which didn't reveal a definitive source but did shed new light on the events.

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China probe says SARS-CoV-2 jump from go-between host most likely

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Time from Start of Quarantine to SARS-CoV-2 Positive Test Among Quarantined College and University Athletes — 17 States, June–October 2020

1,2; Meaghan L. Peterson, MPH2; Mackenzie Malone, MPH2; Margaret A.

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Study finds new evidence of SARS-CoV-2 damaging brain blood vessels

fever, sore throat, cough, and dyspnea, all manifestations of a respiratory illness.However, a spectrum of other clinical manifestations, including headaches, abdominal pain, diarrhea, and loss of taste and smell, have been reported.

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Options to Reduce Quarantine for Contacts of Persons with SARS-CoV-2 Infection Using Symptom Monitoring and Diagnostic Testing

1) never develop symptomatic illness but can still transmit the virus. In this context, quarantine is a critical measure to control transmission.Quarantine is intended to reduce the risk that infected persons might unknowingly transmit infection to others.

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Do SARS-CoV-2 mutations affect its transmissibility?

Nature Communications, may be valuable in helping scientists keep track of the virus’s possible mutations as it encounters people who have been vaccinated against it.Stay informed with live updates on the current COVID-19 outbreak and visit our coronavirus hub for more advice on prevention and treatment.SARS-CoV-2, the virus responsible for COVID-19, has been present in humans for approximately 1 year. During that time, though, it has not stayed the same.Viruses spread by replicating themselves within a host organism.

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Implementation of a Pooled Surveillance Testing Program for Asymptomatic SARS-CoV-2 Infections on a College Campus — Duke University, Durham, North Carolina, August 2–October 11, 2020

1; Laura Andrews, MS2; Mattia Bonsignori, MD3; Kyle Cavanaugh, MBA4; Michael B. Datto, MD, PhD5; Anastasia Deckard, PhD6; C. Todd DeMarco1; Nicole DeNaeyer1; Carol A.

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Transmission of SARS-COV-2 Infections in Households — Tennessee and Wisconsin, April–September 2020

1,*; Melissa A. Rolfes, PhD2,*; Yuwei Zhu, MD1; Huong Q.

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SARS-CoV-2 may be able to infect a significant number of mammals

SARS-CoV-2 could theoretically infect a large number of mammals.The research, which appears in the journal Scientific Reports, identifies important animal species that should be the focus of future real-world observations.Stay informed with live updates on the current COVID-19 outbreak and visit our coronavirus hub for more advice on prevention and treatment.Central to scientific efforts to reduce the effects of the COVID-19 pandemic is the development of a vaccine.Suppose an effective vaccine can be developed and made widely available to a significant number of people worldwide.

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Scientific Brief: SARS-CoV-2 and Potential Airborne Transmission

particle (e.g., droplet, dust, pollen) capable of travel through the air. For respiratory droplets, that can include droplets that are close to the source and those that have moved farther away.

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Asymptomatic and Presymptomatic SARS-CoV-2 Infections in Residents of a Long-Term Care Skilled Nursing Facility — King County, Washington, March 2020

On March 27, 2020, this report was posted online as an MMWR Early Release.Anne Kimball, MD1,2; Kelly M. Hatfield, MSPH1; Melissa Arons, MSc1,2; Allison James, PhD1,2; Joanne Taylor, PhD1,2; Kevin Spicer, MD1; Ana C. Bardossy, MD1,2; Lisa P.

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SARS-CoV-2 Infections and Serologic Responses from a Sample of U.S. Navy Service Members — USS Theodore Roosevelt, April 2020

On June 9, 2020, this report was posted online as an MMWR Early Release.Daniel C. Payne, PhD1; Sarah E. Smith-Jeffcoat, MPH1; Gosia Nowak, MPH2; Uzo Chukwuma, MPH2; Jesse R.

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Detection and Genetic Characterization of Community-Based SARS-CoV-2 Infections — New York City, March 2020

1,2; Karen A. Alroy, DVM1,2; Sharon K. Greene, PhD1; Page Keating, MSPH1; Amanda Wahnich, MPH1; Don Weiss, MD1; Preeti Pathela, DrPH1; Christy Harrison, PhD3; Jennifer Rakeman, PhD3; Gayle Langley, MD4; Suxiang Tong, PhD4; Ying Tao, PhD4; Anna Uehara, PhD4; Krista Queen, PhD4; Clinton R.

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Considerations for Use of SARS-CoV-2 Antigen Testing in Nursing Homes

Overview of Testing for SARS-CoV-2Interim Guidance for Rapid Antigen Testing for SARS-CoV-2Interim SARS-CoV-2 Testing Guidelines for Nursing Home Residents and Healthcare PersonnelInterim Guidance on Testing Healthcare Personnel for SARS-CoV-2Interpreting Results of Diagnostic TestsThis document provides a summary of considerations for use of SARS-CoV-2 (the virus that causes COVID-19) antigen testing in nursing homes and is intended for nursing home providers and state and local public health departments.Antigen tests are available as point-of-care (POC) diagnostics for SARS-CoV-2. They have a rapid turnaround time, which is critical to the identification of SARS-CoV-2 infection and rapid implementation of infection prevention and control

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Dr. Robert R. Redfield Statement on “Preventing and Mitigating SARS-CoV-2 Transmission — Four Overnight Camps, Maine, June–August 2020”

Media Relations (404) 639-3286Today’s MMWR, which highlights the thoughtful and prudent public health practices used during overnight summer camps in Maine, reinforces how powerful everyday preventive actions are in reducing and keeping COVID-19 transmission low.

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Duo of antiviral drugs strongly inhibits SARS-CoV-2 in the lab

Nature, means that doctors can immediately start treating hospitalized patients with dexamethasone. This is a cheap, readily available steroid that has been in widespread use for decades.Stay informed with live updates on the current COVID-19 outbreak and visit our coronavirus hub for more advice on prevention and treatment.Drugs with a proven safety record, such as dexamethasone, have a clear advantage over novel treatments and vaccines; after a relatively swift clinical trial, national drug regulators can immediately approve their use.

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No evidence that mutations to SARS-CoV-2 increase transmissibility

An analysis of more than 15,000 SARS-CoV-2 genomes finds that mutations to the virus do not increase its transmissibility and are instead either neutral or detrimental to its spread.

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pharmaceutical-technology.com

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Researchers identify antibody with activity against SARS-CoV-2 in lab

Researchers at Utrecht University and Erasmus Medical Center in the Netherlands, in alliance with China-based firm Harbour BioMed, have identified a fully human monoclonal antibody with activity against the novel coronavirus, SARS-CoV-2.

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New study questions the effectiveness of masks against SARS-CoV-2

Research published at the beginning of April casts serious doubts about the effectiveness of both surgical and cloth masks in preventing the spread of infectious SARS-CoV-2 particles.

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Cats may be able to contract SARS-CoV-2, but evidence is limited

A preliminary study suggests that cats can contract the new coronavirus, yet this happened in an artificial context where scientists gave the felines high doses of SARS-CoV-2. The research did not prove convincingly that cats were able to transmit the virus further, between themselves or to humans.

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CDC Grows SARS-CoV-2, the virus that causes COVID-19, in Cell Culture

Virus isolates will be used for research by the scientific and medical community

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United States	Cases: 46 252 513 Deaths: 750 423 Recovered: 0
India	Cases: 34 321 025 Deaths: 459 652 Recovered: 0
Brazil	Cases: 21 835 785 Deaths: 608 235 Recovered: 0
United Kingdom	Cases: 9 215 683 Deaths: 141 607 Recovered: 0
Russia	Cases: 8 494 589 Deaths: 237 619 Recovered: 0

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