Proton pump inhibitors (PPIs), which treat acid reflux, peptic ulcers, and indigestion, are among the world’s most widely prescribed drugs.The drugs, including omeprazole and lansoprazole, reduce the amount of acid produced by specialized cells in the stomach lining.Most medical professionals believe that short-term use of PPIs is safe, but many have concerns about long-term use.
Some studies have linked the drugs to an increased risk of fractures, chronic kidney disease, pneumonia, gut infections, and dementia.