NIH stops 2 hydroxychloroquine COVID-19 trialsThe National Institutes of Health (NIH) announced over the weekend that it has stopped two randomized clinical trials exploring the use of the antimalaria drug hydroxychloroquine for treating and preventing COVID-19.The NIH halted the ORCHID study, which was evaluating the safety and effectiveness of hydroxychloroquine in adults hospitalized with COVID-19, after a data safety and monitoring board met late Friday and determined that while the drug had caused no harm, it was unlikely to benefit hospitalized patients.
More than 470 patients were enrolled in the blinded, placebo-controlled trial when it was stopped. All patients will continue to receive standard care.The other trial, conducted by
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