The number of Covid-related deaths reduced dramatically between February and March as HSE Chief Executive Paul Reid praised the "significant impacts" of the vaccination programme.
There have been 194 deaths linked to coronavirus notified to the Department of Health so far for March, compared to 831 for February.
This is a reduction in mortality rates of 76% month-on-month. However, some Covid-related deaths for February and March may not yet have been notified to the department.
Mr Reid told RTÉ: "The vaccination programme is showing significant benefits for the most vulnerable [who have been] vaccinated to date." He said the vaccinations had led to "reduced levels of sickness, hospitalisations and mortality for the older population".