To slay the larger cancer cell they are attached to, the two smaller killer T cells release protein bombs. By Mitch LeslieOur immune system’s killer T cells earn their name.
They destroy infected and cancerous cells, and now, research reveals new details about how they do it. The cells bombard their targets with protein “bombs” packed with deadly chemicals.The study “is clearly a significant step forward in refining our knowledge” about how these immune sentinels take out dangerous cells, says immunologist David Masopust of the University of Minnesota Medical School.One of a killer T cell’s most important weapons is perforin, a protein that punctures the outer membrane of the target cell.