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On-off dosing of cancer drugs does not help melanoma patients

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www.sciencemag.org
sciencemag.org:

Taking breaks from melanoma drugs didn’t slow the growth of patients’ tumors in a clinical trial (here, a malignant melanoma cell within skin tissue).

By Jocelyn KaiserDrugs that home in on and block cell growth signals can dramatically shrink tumors, but all too often the cancer comes back.

An attention-grabbing mouse study 7 years ago suggested that these targeted drugs would work better at shrinking melanoma tumors if cancer patients got a break from their medicine every few weeks.The first large trial to test this idea, however, has found that melanoma tumors grew back faster when patients were on such an “intermittent” dosing schedule.

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strain
COVID-19
United States
United States
Cases: 46 252 513
Deaths: 750 423
Recovered: 0
India
India
Cases: 34 321 025
Deaths: 459 652
Recovered: 0
Brazil
Brazil
Cases: 21 835 785
Deaths: 608 235
Recovered: 0
United Kingdom
United Kingdom
Cases: 9 215 683
Deaths: 141 607
Recovered: 0
Russia
Russia
Cases: 8 494 589
Deaths: 237 619
Recovered: 0
Detail statistic
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