Sex and gender exist on spectrums. This article will use the terms “male” and “female” to refer to a person’s sex assigned at birth.The Pfizer-BioNTech COVID-19 vaccine, named BNT162b2, and known as Comirnaty in the European Union, is a two-dose mRNA vaccine developed by two pharmaceutical industry companies: Pfizer in the United States and BioNTech in Germany.In December 2020, the Food and Drug Administration (FDA) and World Health Organization (WHO) authorized the vaccine for emergency use in individuals aged 16 years and older, making it the first COVID-19 vaccine to receive emergency use authorization by either organization.