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Sustained psychological distress may be tied to long COVID

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Among a cohort who never had COVID-19 but tested positive within 1 year after baseline, depression, anxiety, stress, loneliness, and concerns about infection were linked to a 33% to 50% increased risk of self-reported postinfection symptoms lasting at least 4 weeks, as well as functional impairment, finds a study published today in JAMA Psychiatry."We were surprised by how strongly psychological distress before a COVID-19 infection was associated with an increased risk of long COVID," said first author Siwen Wang, MD, a researcher in the Department of Nutrition at Harvard T.H.

Chan School of Public Health, in a Harvard news release. "Distress was more strongly associated with developing long COVID than physical health risk factors such as obesity, asthma, and hypertension."A team led by Clarkson University researchers analyzed data from three large ongoing, predominantly female Nurses' Health Study II, Nurses' Health Study 3, and the Growing Up Today Study.

Participants completed at least one follow-up survey about their symptoms, COVID-19 test results, and any related hospitalizations from April 2020 to November 2021 (6 monthly, then quarterly for 336 days).

Median time from baseline to infection was 30 weeks.More distress, more riskAmong 54,960 participants, average age was 57.5 years, 96.5% were White, 38.0% were active healthcare workers, 96.6% were female, and 6% tested positive for COVID-19 during follow-up.Among the 3,193 participants with a positive test result, all types of distress were significantly tied to an increased risk of long-COVID conditions in a dose-dependent manner after adjustment for demographic factors.

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Los Angeles Unified School District, officials confirmed Sunday.The data was released Saturday -- two days before a deadline previously given by the hackers -- in an apparent response to LAUSD Superintendent Alberto Carvalho's stated refusal to pay ransom to an international hacking syndicate, the Los Angeles Times reported.The newspaper said it reviewed screenshots from the hack that appeared to show some Social Security numbers, but the full extent of the release was not clear.District spokeswoman Shannon Haber would not confirm the release when reached by City News Service on Sunday.The group claiming responsibility for the cyberattack had set a Monday deadline for the district to pay a ransom to the organization.In a dark web post detected and reprinted by Brett Callow of the cybersecurity firm Emsisoft, the hacking syndicate Vice Society listed the LAUSD as one of "our partners," and stated, "The papers will be published by London time on October 4, 2022 at 12:00 a.m."The post did not give any indication about what information had been obtained or what would be published.Carvalho previously acknowledged that the district received a ransom demand from the group responsible for the Labor Day weekend hack -- which he declined to name."We can acknowledge ... that there has been communication from this actor (hacker) and we have been responsive without engaging in any type of negotiations," he told reporters.
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