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To aid vaccine research, U.K. approves deliberate infections of volunteers with coronavirus

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Jon CohenScience’s COVID-19 reporting is supported by the Heising-Simons Foundation.An ethics board that oversees clinical trials in the United Kingdom today said a research team there can begin to intentionally infect volunteers with the virus that causes COVID-19, a world-first experiment intended to accelerate research into vaccines against the disease.The hotly debated “human challenge” experiment will, as a first step, determine the lowest level of the pandemic coronavirus, SARS-CoV-2, needed to infect the healthy, young volunteers.

The researchers then plan to vaccinate additional volunteers and expose them to that “challenge dose” to assess protection and the immune responses that correlate with it.The human challenge model, long.

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