atherosclerosis (narrowed arteries) and cardiovascular disease. Doctors define severe hypercholesterolemia as untreated LDL cholesterol levels of at least 190 milligrams per deciliter (mg/dl) of blood.Cardiologists in the U.S.
recommend that individuals who are at very high risk of cardiovascular disease due atherosclerosis aim for an LDL cholesterol level of around 70 mg/dl of blood.Lifestyle changes can help reduce LDL, but people usually need to take cholesterol-lowering drugs to reach this goal.
In addition, certain genetic differences can make achieving this objective more difficult for some people.Worldwide, approximately 1 in 250 adults have an inherited condition called heterozygous familial hypercholesterolemia.
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