A cycle of blood clotting and inflammation may contribute to the breathing difficulties of some COVID-19 patients. A forthcoming clinical trial will assess whether a type of drug already approved for the prevention of blood clots after a heart attack or stroke might help prevent these difficulties.
Critically ill patients can develop a severe inflammatory lung condition called acute respiratory distress syndrome (ARDS), which affects their ability to breathe unaided.
The hallmark of ARDS is damage to the lining of the lungs from inflammation that allows fluid to build up in the lungs. This inflammation activates increased coagulation within the small vessels of the lungs.