Hospitalization for COVID-19 tied to 45% higher risk of heart failureCOVID-19 hospitalization is associated with a 45% greater risk of subsequent heart failure (HF), particularly for patients who are younger, White, or previously diagnosed as having heart disease, according to a US study published late last week in Nature Communications.A University of Arkansas researcher led the study of 587,330 patients hospitalized from Mar 1, 2020, to Mar 31, 2022, using data from the National COVID Cohort Collaborative Study.
Of those patients, 257,075 tested positive for COVID-19. The COVID-19 patients were older (51 vs 46 years), more likely to be male (49% vs 42%), and less likely to be White (61% vs 69%).During a median of 367 days of follow-up, 10,979 patients developed HF, and 17,641 died of any cause.
In adjusted analyses, COVID-19 was tied to a 45% higher risk of HF (hazard ratio, 1.45; 95% confidence interval, 1.39 to 1.51), with the greatest risk among younger and White patients and those with established cardiovascular disease.Relative to non-COVID patients, infected patients had a higher rate of new diagnoses of HF (2.3% vs.
1.5%), death (3.3% vs. 2.6%), and composite death or new HF (5.2% vs. 4.0%) after hospital release.The crude HF rate was higher for COVID-19 patients, at 2.55 vs 1.44 events per 100 person-years.