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Santhera explores lonodelestat to treat ARDS in Covid-19 patients

covid-19 experts patient Coronavirus
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www.pharmaceutical-technology.com
pharmaceutical-technology.com:

Swiss-based Santhera Pharmaceuticals has partnered with Cold Spring Harbor Laboratory (CSHL) to explore the use of lonodelestat (POL6014) as a potential treatment for acute respiratory distress syndrome (ARDS) caused by Covid-19.

CSHL researchers joined a new consortium of international non-clinical and clinical experts called ‘NETwork to target neutrophils in Covid-19’.

The consortium will analyse the role of neutrophils and neutrophil extracellular traps (NETs) in the Covid-19 pathology, while also investigating hNE and other targets for the treatment of the novel coronavirus infection.

NETs are macromolecular DNA structures and proteins that neutrophils can expel; hNE is generated by neutrophils during NETs formation.

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