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Scientists identify potential drug candidate against COVID-19

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www.livemint.com

Washington: Using state-of-the-art computer simulations, scientists have identified a preexisting drug, used to treat multiple diseases, including bipolar disorders and hearing loss, that could prevent the novel coronavirus from replicating in host cells, an advance that may lead to a therapeutic solution against COVID-19.The study, published in the journal Science Advances, assessed the molecule main protease, Mpro, of the novel coronavirus which is a key enzyme that plays a central role in its life cycle.According to the researchers, including those from the University of Chicago in the US, Mpro facilitates the virus' ability to make proteins from its genetic material -- RNA -- and enables the pathogen to replicate within the host.

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