How long will the booster’s protection last? Antibodies from a booster shot will wane over time—but that doesn’t mean your immune protection has disappeared.
Antibody levels decline with all vaccines, scientists say. The body produces an initial burst of antibodies, peaking one or two weeks after a booster shot.
Levels then decline and eventually stabilize, says John Wherry, director of the Institute for Immunology at the University of Pennsylvania.
Covid-19 vaccines haven’t been around long enough to study long-term immunity over several years, either from the initial shots or boosters.