PLOS Medicine, may help guide doctors giving nutritional advice to people with coronary heart disease.As the Centers for Disease Control and Prevention (CDC) report, heart disease accounts for around 1 in 4 deaths in the United States, making it the leading cause of death.Having high blood pressure, high cholesterol, or smoking increases the chances of developing heart disease, and having the disease increases the risk of cardiovascular events, such as heart attacks, arrhythmia, or heart failure.Modifying the diet is a key way to reduce the risk of heart disease.For many years, researchers have demonstrated the benefits of a Mediterranean diet on heart health.