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Incyte begins Phase III trial of ruxolitinib to treat Covid-19

Usa covid-19 infection patient Coronavirus
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www.pharmaceutical-technology.com
pharmaceutical-technology.com:

Incyte has started a Phase III clinical trial of ruxolitinib (Jakafi) to treat cytokine storm caused by Covid-19 coronavirus infection.

Cytokine storm is an immune overreaction to a viral infection and can result in serious complications such as pneumonia and acute respiratory distress syndrome (ARDS).

Ruxolitinib is a JAK1/JAK2 inhibitor approved for polycythemia vera, myelofibrosis and graft-versus-host disease. The global, randomised, double-blind, placebo-controlled Phase III trial, named RUXCOVID, will assess the safety and efficacy of ruxolitinib given along with standard-of-care (SoC) in around 400 patients aged ≥12 years worldwide.

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COVID-19
United States
United States
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Deaths: 750 423
Recovered: 0
India
India
Cases: 34 321 025
Deaths: 459 652
Recovered: 0
Brazil
Brazil
Cases: 21 835 785
Deaths: 608 235
Recovered: 0
United Kingdom
United Kingdom
Cases: 9 215 683
Deaths: 141 607
Recovered: 0
Russia
Russia
Cases: 8 494 589
Deaths: 237 619
Recovered: 0
Detail statistic
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