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Statins: Negative expectations may cause side effects

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statin reduces the chances of having a heart attack or stroke by lowering the amount of cholesterol in their blood.Researchers estimate that almost 30% of people over 40 in the United States take a statin.

Most people tolerate these drugs well, but many stop taking them after reporting side effects such as muscle aches, fatigue, and joint pain.However, according to a 2014 review of clinical trials that compared statins with a placebo, or “dummy pill” — only a small proportion of the reported symptoms were actually caused by the drugs.Some symptoms, such as aches and pains, may result from normal aging, the nocebo effect, or an interaction between the two.Most people are familiar with the way that positive expectations about a treatment can.

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