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Clinical trials press on for conditions other than COVID-19. Will the pandemic’s effects sneak into their data?

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Amid COVID-19 precautions, medical centers continue to treat patients with other serious conditions. By Kelly ServickScience's COVID-19 reporting is supported by the Pulitzer Center.Myron Cohen has run clinical trials through hurricanes and civil unrest.

Now, the infectious disease researcher at the University of North Carolina, Chapel Hill, says he and his colleagues are in a new situation: trying to carry out large, international trials in the midst of coronavirus lockdowns.

Cohen co-leads a network of HIV prevention trials, some of which have paused during the pandemic. But for other studies, he says, “stopping would be of grave consequence” to participants.

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Omicron 75% less likely to cause death than Delta COVID-19 variant: South Korean data
Omicron coronavirus variant are nearly 75% less likely to develop serious illness or die than those who contract the Delta variant, real world data released on Monday by South Korea’s health authorities showed.A study by the Korea Disease Control and Prevention Agency (KDCA) of some 67,200 infections confirmed since December showed the Omicron variant’s severity and death rates averaged 0.38% and 0.18%, respectively, compared with 1.4% and 0.7% for the Delta cases.The KDCA classed severe cases as people who were hospitalised in intensive care units. COVID cases exceed 400 million globally as Omicrons spreads Around 56% of 1,073 people who died over the past five weeks were either unvaccinated or had received only one dose, the study showed, with people aged 60 or older accounting for 94% of deaths.More than 86% of South Korea’s 52 million population have been double vaccinated and nearly 60% have received a booster shot.South Korea had kept cases and deaths relatively low thanks to widespread social distancing measures and aggressive testing and tracing.The Omicron variant has led to a surge in cases — daily new infections topped a record 100,000 last week — but authorities have pushed ahead with slightly easing social distancing rules amid the lower fatality rate and ahead of a presidential election next month.Contact tracing and mandatory isolation for vaccinated people was scrapped in favour of self diagnosis and at-home treatment to free up medical resources.
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