GUWAHATI : Four more COVID-19 patients, including a senior doctor of the Gauhati Medical College Hospital (GMCH), died and 1,001 new cases were reported on Monday, taking Assam's infection tally to 17,807, Health Minister Himanta Biswa Sarma said.The death toll of novel coronavirus patients in the state has risen to 45 but the Death Audit Board is yet to ascertain whether five of these had the "underlying cause of death" as COVID-19.The state has reported 1,001 new cases and out of these, 513 are from Guwahati, Sarma said.This is the second highest single-day spike in cases so far, he said.The highest single-day spike of 1,202 cases was reported on July 4.