Sign up here for GlobalData's free bi-weekly Covid-19 report on the latest information your industry needs to know.UK-based biotechnology firm Tiziana Life Sciences has executed an agreement with STC Biologics for the manufacture of TZLS-501 for clinical studies in Covid-19 patients.
TZLS-501 is an anti-IL-6 receptor (anti-IL-6R) monoclonal antibody (mAb) acquired from Novimmune in 2017. Currently, the drug is in agreement with Bristol Myers Squibb (BMS).
It acts by inhibiting downstream signalling pathways from membrane-bound and soluble IL-6 receptors, as well as rapidly decreases blood-stream levels of IL-6, involved in cytokine release syndrome (CRS) in lungs of Covid-19 patients.