RNA prevention patient

Newly identified cell type may help predict, treat rheumatoid arthritis flares

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www.sciencemag.org

Eli CahanWhen Dana Orange’s patients experience flare-ups of rheumatoid arthritis (RA), they can be devastating. One woman’s pain is so great that she can’t bend her elbow to brush her teeth.

Another is unable to support the weight of her purse. Still another takes 30 minutes to roll out of bed and 90 minutes more bath and dress.But the worst part, says Orange, a rheumatologist at the Rockefeller University, is that these attacks are wholly unpredictable.

A new study may change that. Orange and her colleagues found that in the weeks before an RA attack, a newly identified cell type builds up in the blood, possibly triggering inflammation in the joints.

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