A retrospective single-center case series of 50 hospitalized pediatric COVID-19 patients in New York City found that respiratory symptoms were common but not ubiquitous, that most children had underlying illnesses, and that obese patients were likely to require mechanical ventilation.A separate single-center case series published today in JAMA Network Open found that that pediatric COVID-19 patients with moderate disease had higher levels of the inflammatory marker interleukin 10 and lower levels of neutrophil immune cells than those with mild illness, suggesting that the virus may be associated with abnormal immune responses.Obesity, inflammation, mechanical ventilationThe first study, published today in JAMA Pediatrics, involved patients