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Three big studies dim hopes that hydroxychloroquine can treat or prevent COVID-19

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www.sciencemag.org

Kai KupferschmidtScience’s COVID-19 reporting is supported by the Pulitzer Center.Through the fog of alleged misconduct, hope, hype, and politicization that surrounds hydroxychloroquine, the malaria drug touted as a COVID-19 treatment, a scientific picture is now emerging.Praised by presidents as a potential miracle cure and dismissed by others as a deadly distraction, hydroxychloroquine was spared a seeming death blow last week.

On 4 June, after critics challenged the data, The Lancet suddenly retracted a paper that had suggested the drug increased the death rate in COVID-19 patients, a finding that had stopped many clinical trials in their tracks.

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