WASHINGTON – Trying to close out major unfinished business, the Trump administration issued regulations Friday that could lower the prices Americans pay for many prescription drugs.But in a time of political uncertainty, it’s hard to say whether the rules will withstand expected legal challenges from the pharmaceutical industry or whether the incoming Biden administration will accept, amend or try to roll them back entirely.President Donald Trump was announcing the new policy at a White House event.The two finalized rules, long in the making, would:— tie what Medicare pays for medications administered in a doctor's office to the lowest price paid among a group of other economically advanced countries.