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EndeavorOTC is an over-the-counter digital therapeutic authorized by the Food and Drug Administration (FDA) for the treatment of adults 18 and older with primarily inattentive or combined-type ADHD.

In the U.S., it is indicated to improve attention and functioning as measured by computer-based testing. It is available without a prescription.EndeavorOTC is not intended to be used as a stand-alone therapeutic and is not a substitution for ADHD medication.Developed by Akili Interactive, EndeavorOTC is the first FDA-authorized over-the-counter digital therapeutic treatment for adult ADHD.

It uses the same proprietary technology as EndeavorRx, an FDA-approved digital therapeutic for the treatment of children ages 8 to 12 with primarily inattentive or combined-type ADHD.EndeavorOTC is available in the U.S.

in the Apple App Store for iOS and the Google Play Store for Android mobile devices.Through its immersive video game experience, EndeavorOTC presents specific sensory stimuli and simultaneous motor challenges designed to alter pathways in the brain related to focus.Adults typically interact with EndeavorOTC on mobile devices for 25 minutes daily, five days a week.The EndeavorOTC games, which challenge players to simultaneously target and navigate through a series of obstacles, are designed to boost cognitive functions related to attention, focus, multitasking, and prioritization.The clinical study supporting EndeavorOTC’s FDA clearance found that, after six weeks of EndeavorOTC use, 83% of participants saw clinical improvements in their ability to focus as measured by the TOVA attentional control score.

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