Multisystem inflammatory syndrome in children (MIS-C) is rare among 12- to 20-year-olds who have received COVID-19 vaccination, a study yesterday in The Lancet Child & Adolescent Health suggests.The study was based on 9 months of follow-up data on US children and young adults ages 12 to 20 who had received at least one dose of the Pfizer-BioNTech COVID vaccine from Dec 14, 2020, to Aug 31, 2021.Only 21 cases out of more than 21 million vaccinated adolescents developed the rare disorder, which mimics Kawasaki's, during the follow-up period.
Fifteen of the 21 were diagnosed as having COVID-19 despite vaccination, while 6 developed MIS-C for unknown reasons."Our results suggest that MIS-C cases following COVID-19 vaccination are rare and that the likelihood of developing MIS-C is much greater in children who are unvaccinated and get COVID-19.
COVID-19 vaccination is recommended for everyone aged 5 years and older in the United States for the prevention of COVID-19," said Anna R.
Yousaf, MD, the lead author and a researcher at the Centers for Disease Control and Prevention (CDC), in a Lancet press release.No deaths, 12 ICU admissionsOf the 21 patients, all were admitted to the hospital, with 12 requiring admission to the intensive care unit (ICU).