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Small study of rectal cancer treatment brings every single patient into remission

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FILE - Rectal Carcinoma. Abdominal X-Ray In Front View. (Photo By BSIP/UIG Via Getty Images) A small U.S. study of rectal cancer patients with a certain mutation found that every single person treated with an immunotherapy drug had their cancer "disappear" without the need for further treatment.The small study of 12 patients and counting was conducted by oncology researchers at Memorial Sloan Kettering Cancer Center (MSK) in New York.

In every case, the rectal cancer patients went into remission after being treated with the experimental immunotherapy drug, called dostarlimab, for six months, MSK said in a statement.

Furthermore, the patients didn’t need standard treatments of radiation, surgery, or chemotherapy. The cancer, which begins in the last several inches of the large intestine, has not returned in any of the patients, who have remained cancer-free for up to two years to date.The results of the small trial were published this week in The New England Journal of Medicine and featured at the nation’s largest gathering of clinical oncologists in June 2022."It’s really exciting," MSK medical oncologist and trial leader Dr.

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Dearth of downtown workers means end of the line for Winnipeg restaurant after 40+ years - globalnews.ca - city Downtown - city Detroit - city Sandwich
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Dearth of downtown workers means end of the line for Winnipeg restaurant after 40+ years
COVID-19 pandemic.Downtown staple Nathan Detroit’s Sandwich Pad will be closing for good later this month after more than four decades in business.The eatery, located in the underground beneath the Fairmont Hotel and the Richardson building, said much of its business comes from downtown workers — a group that hasn’t fully rebounded since the pandemic began.Brenlea Yamron, who runs Nathan Detroit’s with her sister Karen after taking over from their late father 20 years ago, told 680 CJOB’s The Start that the outpouring of support from the public is making the tough decision a little easier.“It’s hard, but we are so enjoying all that Nathan’s has given our family,” Yamron said.“We’re so incredibly overwhelmed by the people out there. We are lovers of Winnipeg, we are promoters of Winnipeg — we’ve all raised our families in Winnipeg.“Winnipeg … man, are you making us proud right now.”Yamron said that while the closure will give their mother, Fraydel, the opportunity to finally retire after 40+ years, the future remains unwritten for the sisters.“My sister and I are definitely way too young to retire, so we’re going to be looking for something else,” she said.“Whatever it’ll be, we’ll enjoy hopefully a little time off and then start looking — but it will definitely be in Winnipeg.”The restaurant will be making an announcement in the near future about the plans for Nathan Detroit’s final days.The president of the Winnipeg Chamber of Commerce says it’s a simple fact that businesses like Nathan Detroit’s need more people downtown in order to stay open, and that as more and more businesses take on debt to make it through, many have reached their limit.
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