Today the New England Journal of Medicine published two studies spotlighting the serious manifestations of COVID-19–related multisystem inflammatory syndrome in children (MIS-C), the first involving 186 kids in 26 states and the second involving 99 patients in New York.On May 14, the Centers for Disease Control and Prevention (CDC) issued a national health advisory on COVID-19 patients with features of MIS-C similar to Kawasaki disease, a rare pediatric inflammatory illness that can cause coronary-artery aneurysms and toxic shock syndrome.Both studies revealed the same high level of intensive care: 80%.Severe symptoms, delayed onsetIn the first study, a CDC-led team conducting retrospective and prospective surveillance of US pediatric