restrictions can be cautiously eased in the coming weeks, saying vaccines are providing “grounds for confidence”. The Prime Minister said he wants the end of current national lockdown to be “irreversible” ahead of the publication of his “road map” next Monday.Get the latest updates from across Greater Manchester direct to your inbox with the free MEN newsletterYou can sign up very simply by following the instructions hereThis week, he will analyse data on case numbers, hospital admissions, deaths and the impact of the vaccine roll-out as he prepares his plan.Mr Zahawi said early signs from Oxford University has been promising but PHE research – the Vivaldi study on care home residents and staff, and the Siren research on healthcare workers.